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GTX49195
Nucleophosmin antibody [2D9-C3-E5]
Cannot supply to this region.
- SKU:
- GTX49195
- Additional Names:
- nucleophosmin 1 , B23 , NPM
- Application:
- WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.5% BSA, 50% glycerol, 0.02% Sodium azide.
- Immunogen:
- Purified recombinant full length of human NPM1 protein expressed in E.coli.
- Clone:
- 2D9-C3-E5
- Uniprot:
- P06748
- Synonyms:
- B23;NPM;Nucleolar phosphoprotein B23;nucleolar protein NO38;nucleophosmin;nucleophosmin (nucleolar phosphoprotein B23, numatrin);nucleophosmin/nucleoplasmin family, member 1;Numatrin;testicular tissue protein Li 128
- Extra Details:
- The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
- Shipping Conditions:
- Blue Ice