GTX49069
KCNQ4 antibody, Internal
Cannot supply to this region.
- SKU:
- GTX49069
- Additional Names:
- potassium voltage-gated channel subfamily Q member 4 , DFNA2 , DFNA2A , KV7.4
- Application:
- WB
- Concentration:
- 0.5-1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Hamster, Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to an Internal region of Human KCNQ4.
- Uniprot:
- P56696
- Synonyms:
- DFNA2;DFNA2A;KQT-like 4;KV7.4;potassium channel KQT-like 4;potassium channel subunit alpha KvLQT4;potassium channel, voltage gated KQT-like subfamily Q, member 4;potassium voltage-gated channel subfamily KQT member 4;potassium voltage-gated channel, KQT-like subfamily, member 4;Voltage-gated potassium channel subunit Kv7.4
- Extra Details:
- The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice