GNPTAB antibody, N-term

Cannot supply to this region.

SKU:: GTX49030
Additional Names:: N-acetylglucosamine-1-phosphate transferase subunits alpha and beta , GNPTA , ICD
Application:: WB
Concentration:: 0.5-1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 2% Sucrose, 0.09% Sodium azide.
Immunogen:: A synthetic peptide corresponding to a N-terminal region of Human GNPTAB
Uniprot:: Q3T906
Synonyms:: GlcNAc phosphotransferase;glcNAc-1-phosphotransferase subunits alpha/beta;glucosamine (UDP-N-acetyl)-lysosomal-enzyme N-acetylglucosamine phosphotransferase;GNPTA;ICD;N-acetylglucosamine-1-phosphate transferase alpha and beta subunits;N-acetylglucosamine-1-phosphotransferase subunits alpha/beta;stealth protein GNPTAB;UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta;UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosamine
Extra Details:: This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010]

Shipping Conditions:: Blue Ice