GTX48937
Choroideremia antibody, N-term
Cannot supply to this region.
- SKU:
- GTX48937
- Additional Names:
- CHM Rab escort protein , DXS540 , GGTA , HSD-32 , REP-1 , TCD
- Application:
- WB
- Concentration:
- 0.5-1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a N-terminal region of Human Choroideremia
- Uniprot:
- P24386
- Synonyms:
- CHM, Rab escort protein 1;choroideremia (Rab escort protein 1);Choroideremia protein;DXS540;GGTA;HSD-32;Rab escort protein 1;rab proteins geranylgeranyltransferase component A 1;REP-1;TCD;TCD protein
- Extra Details:
- This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
- Shipping Conditions:
- Blue Ice