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  2. Monoclonal

GTX48761

ESRP1 antibody [27H12]

Cannot supply to this region.

SKU:
GTX48761
Additional Names:
epithelial splicing regulatory protein 1 , 2210008M09Rik , A630065D16 , BC031468 , Rbm35a
Application:
ELISA, WB
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Mouse
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Mouse
Buffer:
20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
Immunogen:
Full length recombinant mouse Esrp-1 fusion protein.
Clone:
27H12
Uniprot:
Q3US41
Synonyms:
2210008M09Rik;A630065D16;BC031468;epithelial splicing regulatory protein 1;Rbm3;Rbm35a;RNA binding motif protein 35A;RNA-binding motif protein 35A;RNA-binding protein 35A
Extra Details:
Epithelial splicing regulatory protein 1 (Esrp-1) is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2, and also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). EsrpP-1 acts by directly binding specific sequences in mRNAs. It binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Shipping Conditions:
Blue Ice