GTX48696
Iaspp antibody
Cannot supply to this region.
- SKU:
- GTX48696
- Additional Names:
- protein phosphatase 1 regulatory subunit 13 like , IASPP , NKIP1 , RAI , RAI4
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1.1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to an internal region near amino acids 775-800 of human Iaspp (isoform 1) protein.
- Uniprot:
- Q8WUF5
- Synonyms:
- IASPP;inhibitor of apoptosis stimulating protein of p53;inhibitor of ASPP protein;NFkB interacting protein 1;NFkB-interacting protein 1;NKIP1;PPP1R13B-like protein;protein iASPP;protein phosphatase 1, regulatory (inhibitor) subunit 13 like;RAI;RAI4;relA-associated inhibitor;retinoic acid induced 4
- Extra Details:
- ASPP proteins (ASPP1, ASPP2 and iASPP) represent a new family of p53 binding proteins. ASPP1 and ASPP2 bind and enhance p53-mediated apoptosis. In contrast, the third member, iASPP, functionally inactivates p53. iASPP (also called protein phosphatase 1 regulatory (inhibitor) subunit 13 like protein, Inhibitor of ASPP protein, Protein iASPP, PPP1R13B-like protein and NFkB-interacting protein 1) plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. iASPP blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. This protein
- Shipping Conditions:
- Blue Ice