PARC antibody

Cannot supply to this region.

SKU:: GTX48687
Additional Names:: cullin 9 , H7AP1 , PARC
Application:: ELISA, IHC, WB, IP
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: Filtered-steriled serum, 0.01% Sodium azide.
Immunogen:: Synthetic peptide corresponding to amino acids 2503-2517 of Human PARC (C-terminus) coupled to KLH.
Uniprot:: Q8IWT3
Synonyms:: CUL-9;cullin-9;H7AP1;p53-associated parkin-like cytoplasmic protein;PARC;parkin-like cytoplasmic p53 binding protein;UbcH7-associated protein 1
Extra Details:: Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. PARC is a cullin family member that functions as a cytoplasmic anchor protein in p53-associated protein complexes. PARC regulates the subcellular localization of p53 and subsequent function. PARC forms a complex with p53 in the cytoplasm of unstressed cells and interacts with UBCH7 and UBCH8. PARC shows a cytoplasmic localization and is ubiquitously expressed in all tissues with highest expression in testis brain and kidney.