STAT5A (phospho Tyr694) antibody [5F6.F1]

Cannot supply to this region.

SKU:: GTX48648
Additional Names:: signal transducer and activator of transcription 5A , AA959963 , STAT5
Application:: ELISA, WB, IHC-P, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human, Mouse
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
Immunogen:: Synthetic peptide corresponding to residues surrounding Y694 of mouse STAT5a protein.
Clone:: 5F6.F1
Uniprot:: P42230
Synonyms:: AA959963;Mammary gland factor;mammary gland factor STAT5A;signal transducer and activator of transcription 5A;STA;STAT5
Extra Details:: Signal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5a and Stat5s. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus. Ideal for Cancer, Chromatin & Nuclear Signaling and Signal Transduction research.

Shipping Conditions:: Blue Ice