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  2. Monoclonal

GTX48642

Wnt1 antibody [13F9]

Cannot supply to this region.

SKU:
GTX48642
Additional Names:
Wnt family member 1 , BMND16 , INT1 , OI15
Application:
ELISA, WB
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human, Mouse
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Mouse
Buffer:
20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
Immunogen:
Synthetic peptide corresponding to an internal region of human Wnt1 protein.
Clone:
13F9
Uniprot:
P04628
Synonyms:
BMND16;INT1;OI15;proto-oncogene Int-1 homolog;proto-oncogene Wnt-1;wingless-type MMTV integration site family member 1;wingless-type MMTV integration site family, member 1 (oncogene INT1)
Extra Details:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt1 (Wingless-type MMTV integration site family member 1) is a member of the WNT gene family. It is highly conserved in evolution and the protein encoded by this gene is known to be 98% identical to mouse Wnt1 protein at the amino acid level. Studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. Wnt1 is secreted as an extracellular matrix protein.
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