GTX48591
TDP43 antibody (Biotin)
Cannot supply to this region.
- SKU:
- GTX48591
- Additional Names:
- TAR DNA binding protein , ALS10 , TDP-43
- Application:
- IHC, WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Fish, Human, Mouse
- Buffer:
- PBS, 0.05% Sodium azide.
- Immunogen:
- A synthetic peptide to a C-terminal region [within residues 350-414] of the human TARDBP protein. [Swiss-Prot# Q13148]
- Uniprot:
- Q13148
- Synonyms:
- ALS10;TAR DNA-binding protein 43;TAR DNA-binding protein-43;TDP-43
- Extra Details:
- HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice