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  2. Polyclonal

GTX47114

CYP2B6 antibody, Internal

Cannot supply to this region.

SKU:
GTX47114
Additional Names:
cytochrome P450 family 2 subfamily B member 6 , CPB6 , CYP2B , CYP2B7 , CYP2B7P , CYPIIB6 , EFVM , IIB1 , P450
Application:
WB
Concentration:
0.5-1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 2% Sucrose, 0.09% Sodium azide.
Immunogen:
A synthetic peptide corresponding to an Internal region of Human CYP2B6
Uniprot:
P20813
Synonyms:
1,4-cineole 2-exo-monooxygenase;CPB6;CYP2B;CYP2B7;CYP2B7P;CYPIIB6;cytochrome P450 2B6;cytochrome P450 IIB1;cytochrome P450, family 2, subfamily B, polypeptide 6;cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6;EFVM;IIB1;P450
Extra Details:
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice