GTX46691
Dectin-2 antibody, N-term
Cannot supply to this region.
- SKU:
- GTX46691
- Additional Names:
- C-type lectin domain containing 6A , CLEC4N , CLECSF10 , dectin-2
- Application:
- WB
- Concentration:
- 0.5-1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a N-terminal region of Human CLEC6A
- Uniprot:
- Q6EIG7
- Synonyms:
- C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10;C-type lectin domain family 6 member A;C-type lectin superfamily member 10;CLEC4N;CLECSF10;DC-associated C-type lectin 2;dectin 2;dectin-2;dendritic cell-associated C-type lectin 2;hDECTIN-2
- Extra Details:
- The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
- Shipping Conditions:
- Blue Ice