GTX46586
SPPL2B antibody, N-term
Cannot supply to this region.
- SKU:
- GTX46586
- Additional Names:
- signal peptide peptidase like 2B , IMP-4 , IMP4 , PSH4 , PSL1
- Application:
- WB, IHC-P
- Concentration:
- 0.5-1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a N-terminal region of Human SPPL2B
- Uniprot:
- Q8TCT7
- Synonyms:
- IMP-4;IMP4;intramembrane protease 4;presenilin homologous protein 4;presenilin-like protein 1;PSH4;PSL1;signal peptide peptidase-like 2B;SPP-like 2B
- Extra Details:
- This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice