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  2. Polyclonal

GTX46548

CASPR antibody, N-term

Cannot supply to this region.

SKU:
GTX46548
Additional Names:
contactin associated protein 1 , CASPR , CHN3 , CNTNAP , NRXN4 , P190
Application:
WB
Concentration:
0.5-1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 2% Sucrose, 0.09% Sodium azide.
Immunogen:
A synthetic peptide corresponding to a N-terminal region of Human CNTNAP1
Uniprot:
P78357
Synonyms:
CASPR;caspr1;CHN3;CNTNAP;contactin-associated protein 1;neurexin IV;neurexin-4;NRXN4;P190
Extra Details:
The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009]
Shipping Conditions:
Blue Ice