HS3ST3B1 antibody, N-term

Cannot supply to this region.

SKU:: GTX46416
Additional Names:: heparan sulfate-glucosamine 3-sulfotransferase 3B1 , 3-OST-3B , 3OST3B1 , h3-OST-3B
Application:: WB
Concentration:: 0.5-1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 2% Sucrose, 0.09% Sodium azide.
Immunogen:: A synthetic peptide (38-87 a.a.) corresponding to a N-terminal region of Human HS3ST3B1.
Uniprot:: Q9Y662
Synonyms:: 3-OST-3B;3OST3B1;h3-OST-3B;heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1;heparan sulfate 3-O-sulfotransferase 3B1;heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1;heparan sulfate glucosamine 3-O-sulfotransferase 3B1
Extra Details:: The protein encoded by this gene is a type II integral membrane protein that belongs to the 3-O-sulfotransferases family. These proteins catalyze the addition of sulfate groups at the 3-OH position of glucosamine in heparan sulfate. The substrate specificity of individual members of the family is based on prior modification of the heparan sulfate chain, thus allowing different members of the family to generate binding sites for different proteins on the same heparan sulfate chain. Following treatment with a histone deacetylase inhibitor, expression of this gene is activated in a pancreatic cell line. The increased expression results in promotion of the epithelial-mesenchymal transition. In addition, the modification catalyzed by this protein allows herpes simplex virus membrane fusion and penetration. A very closely related homolog with an almost identical sulfotransferase domain maps less than 1 Mb away. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Shipping Conditions:: Blue Ice