GTX46356
TMEM158 antibody, Internal

Cannot supply to this region.
- SKU:
- GTX46356
- Additional Names:
- transmembrane protein 158 (gene/pseudogene) , BBP , RIS1 , p40BBP
- Application:
- WB
- Concentration:
- 0.5-1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to an Internal region of Human TMEM158
- Uniprot:
- Q8WZ71
- Synonyms:
- 40 kDa BINP-binding protein;BBP;BINP receptor;brain injury-derived neurotrophic peptide (BINP) binding protein;brain specific binding protein;p40BBP;Ras induced senescence 1;Ras-induced senescence protein 1;RIS1;transmembrane protein 158
- Extra Details:
- Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. An allelic polymorphism in this gene results in both functional and non-functional (frameshifted) alleles; the reference genome represents the functional allele. [provided by RefSeq, Jul 2015]
- Shipping Conditions:
- Blue Ice
