GTX45958
HSD3B7 antibody, Internal
Cannot supply to this region.
- SKU:
- GTX45958
- Additional Names:
- hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 , CBAS1 , PFIC4 , SDR11E3
- Application:
- WB
- Concentration:
- 0.5-1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to an Internal region of Human HSD3B7
- Uniprot:
- Q9H2F3
- Synonyms:
- 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase;3 beta-hydroxysteroid dehydrogenase type 7;3 beta-hydroxysteroid dehydrogenase type VII;3-beta-HSD VII;3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase;c(27) 3-beta-HSD;C(27)-3BETA-HSD;CBAS1;cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase;PFIC4;SDR11E3;short chain dehydrogenase/reductase family 11E, member 3
- Extra Details:
- This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
- Shipping Conditions:
- Blue Ice