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  2. Polyclonal

GTX45892

Porimin antibody, C-term

Cannot supply to this region.

SKU:
GTX45892
Additional Names:
transmembrane protein 123 , KCT3 , PORIMIN , PORMIN
Application:
WB
Concentration:
0.5-1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 2% Sucrose, 0.09% Sodium azide.
Immunogen:
A synthetic peptide corresponding to a C-terminal region of Human Porimin.
Uniprot:
Q8N131
Synonyms:
KCT-3;KCT3;keratinocytes associated transmembrane protein 3;Keratinocytes-associated transmembrane protein 3;porimin;PORMIN;pro-oncosis receptor inducing membrane injury;serine/threonine-rich receptor;Transmembrane protein 123
Extra Details:
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice