Skip to content

View Spec Sheet

open_in_new
  1. Shop all
  2. Polyclonal

GTX45033

Protor 1 antibody, C-term

Cannot supply to this region.

SKU:
GTX45033
Additional Names:
proline rich 5 , FLJ20185k , PP610 , PROTOR-1 , PROTOR1
Application:
WB
Concentration:
0.5-1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 2% Sucrose, 0.09% Sodium azide.
Immunogen:
A synthetic peptide corresponding to a C-terminal region of Human Protor 1.
Uniprot:
P85299
Synonyms:
FLJ20185k;PP610;proline rich 5 (renal);proline-rich protein 5;protein observed with Rictor-1;PROTOR-1;PROTOR1;Rho GTPase activating protein 8
Extra Details:
This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]
Shipping Conditions:
Blue Ice