GTX44806
GLP1R antibody
Cannot supply to this region.
- SKU:
- GTX44806
- Additional Names:
- glucagon like peptide 1 receptor , GLP1 , GLP1R
- Application:
- IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Canine, Hamster, Human, Mouse, Porcine, Rabbit, Equine
- Buffer:
- PBS, 0.1% Sodium azide.
- Immunogen:
- Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human GLP1R.
- Uniprot:
- P43220
- Synonyms:
- GLP-1;GLP-1 receptor;GLP-1-R;GLP-1R;GLP1 receptor;glucagon-like peptide 1 receptor;seven transmembrane helix receptor
- Extra Details:
- This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
- Shipping Conditions:
- Blue Ice