AChR beta 2 antibody [270]

Cannot supply to this region.

SKU:: GTX44698
Application:: WB, IF, ICC, IP
Concentration:: 5 mg/ml
Physical State:: Liquid
Species Reactivity:: Avian, Human
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rat
Reactivities:: Human
Buffer:: Ascites, no preservatives.
Immunogen:: Purified neuronal Nicotinic Acetylcholine Receptors from chicken brain.
Clone:: 270
Extra Details:: After binding Acetylcholine, the Nicotinic Acetylcholine Receptor (AChR) responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR seems to be composed of two different type of subunits: alpha and beta. This antibody binds to native subunits as well as denatured subunits although with lower affinity. Clone 270 is useful for immunoisolating and pharmacologically characterizing AChRs, immunopurification of AChRs, and is also useful histologically.