GTX42599
C4d antibody [057-51.5.1.6]
Cannot supply to this region.
- SKU:
- GTX42599
- Additional Names:
- C4AD Antibody , CO4 Antibody , CPAMD2 Antibody , C4A6 Antibody , C4A3 Antibody , complement component 4A (Rodgers blood group) Antibody , C4A Antibody , C4 Antibody , C4S Antibody , RG Antibody , C4A4 Antibody , C4A2 Antibody
- Application:
- ELISA, Flow Cytometry, IHC-Fr
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- Borate buffered saline, 0.1% Sodium azide.
- Immunogen:
- Purified human C4d
- Clone:
- 057-51.5.1.6
- Synonyms:
- acidic C4;acidic complement C4;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2;C4;C4A anaphylatoxin;C4A2;C4A3;C4A4;C4A6;C4AD;C4S;CO4;complement C4-A;complement component 4A (Rodgers blood group);CPAMD2;MHC class III region complement;RG;Rodgers form of C4
- Extra Details:
- This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
- Shipping Conditions:
- Blue Ice