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  2. Polyclonal

GTX41588

GDNF Receptor alpha 1 antibody

Cannot supply to this region.

SKU:
GTX41588
Additional Names:
GDNF family receptor alpha 1 , GDNFR , GDNFRA , GFRA1 , GFRALPHA1 , RET1L , RETL1 , TRNR1 , GDNF Receptor alpha 1
Application:
WB
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 0.02% Sodium azide.
Immunogen:
Peptide corresponding to aa 369- 382 of human GFRA Alpha-1. This peptide sequence is identical to those of mouse and rat.
Uniprot:
P56159
Synonyms:
GDNF family receptor alpha-1;GDNF receptor alpha 1d;GDNF receptor alpha 1e;GDNFR;GDNFR-alpha-1;GDNFRA;GFR-ALPHA-1;GFRalpha-1;Glial cell line-derived neurotrophic factor receptor alpha;GPI-linked anchor protein;PI-linked cell-surface accessory protein;RET ligand 1;RET1L;RETL1;TGF-beta-related neurotrophic factor receptor 1;TRNR1
Extra Details:
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Shipping Conditions:
Blue Ice