GTX40621
S-arrestin antibody [PDS-1]
Cannot supply to this region.
- SKU:
- GTX40621
- Additional Names:
- S-antigen visual arrestin , RP47 , S-AG
- Application:
- WB, IHC-Fr
- Physical State:
- Liquid
- Species Reactivity:
- Porcine
- Purification:
- Protein G Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Bovine, Human, Porcine, Rat
- Buffer:
- PBS, 0.1% Sodium azide.
- Immunogen:
- Porcine S-antigen
- Clone:
- PDS-1
- Uniprot:
- P10523
- Synonyms:
- 48 kDa protein;arrestin 1;Retinal S-antigen;retinal S-antigen (48 KDa protein);rod arrestin;rod photoreceptor arrestin;RP47;S-AG;S-antigen; retina and pineal gland (arrestin);S-arrestin
- Extra Details:
- Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice