GTX39939
IL4 Receptor / CD124 antibody [25463 (49/20)]
Cannot supply to this region.
- SKU:
- GTX39939
- Additional Names:
- interleukin 4 receptor , CD124 , IL-4RA , IL4RA
- Application:
- ELISA, Flow Cytometry, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS, 1% Trehalose, 0.09% Sodium azide.
- Immunogen:
- Spodoptera frugiperda lepidopteran ovarian cell line Sf21-derived, recombinant human interleukin 4 receptor, extracellular domain.
- Clone:
- 25463 (49/20)
- Uniprot:
- P24394
- Synonyms:
- CD124;IL-4 receptor subunit alpha;IL-4RA;IL4R nirs variant 1;IL4RA;interleukin 13 receptor;interleukin-4 receptor alpha chain;interleukin-4 receptor subunit alpha
- Extra Details:
- This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
- Shipping Conditions:
- Blue Ice