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  2. Polyclonal

GTX37568

PDX1 antibody

Cannot supply to this region.

SKU:
GTX37568
Additional Names:
pancreatic and duodenal homeobox 1 , GSF , IDX-1 , IPF1 , IUF1 , MODY4 , PAGEN1 , PDX-1 , STF-1
Application:
IHC-P
Concentration:
0.5 mg/ml
Physical State:
Liquid
Species Reactivity:
Human, Rat
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Rat
Buffer:
10mM TBS, 0.5% BSA, 25% Glycerol, 0.015% ProClin 300.
Immunogen:
KLH conjugated synthetic peptide derived between 198-274 amino acids of human PDX1
Uniprot:
P52945
Synonyms:
glucose-sensitive factor;GSF;IDX-1;Insulin promoter factor 1;insulin promoter factor 1, homeodomain transcription factor;insulin upstream factor 1;IPF-1;IPF1;islet/duodenum homeobox-1;IUF-1;IUF1;MODY4;PAGEN1;pancreas/duodenum homeobox protein 1;pancreatic-duodenal homeobox factor 1;PDX-1;somatostatin transcription factor 1;somatostatin-transactivating factor 1;STF-1
Extra Details:
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]
Shipping Conditions:
Blue Ice