GTX37534
STAT5 antibody
Cannot supply to this region.
- SKU:
- GTX37534
- Additional Names:
- signal transducer and activator of transcription 5A , MGF , STAT5
- Application:
- WB, IHC-P
- Concentration:
- 0.5 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 10mM TBS, 0.5% BSA, 25% Glycerol, 0.015% ProClin 300.
- Immunogen:
- KLH conjugated synthetic peptide derived between 71-150 amino acids of human STAT5
- Uniprot:
- P42229
- Synonyms:
- epididymis secretory sperm binding protein;MGF;signal transducer and activator of transcription 5A;STAT5
- Extra Details:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
- Shipping Conditions:
- Blue Ice