GTX37528
TGF beta 2 antibody
Cannot supply to this region.
- SKU:
- GTX37528
- Additional Names:
- transforming growth factor beta 2 , G-TSF , LDS4 , TGF-beta2
- Application:
- IHC-P
- Concentration:
- 0.5 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 10mM TBS, 0.5% BSA, 25% Glycerol, 0.015% ProClin 300.
- Immunogen:
- KLH conjugated synthetic peptide derived between 164-187 amino acids of human TGF beta 2
- Uniprot:
- P61812
- Synonyms:
- BSC-1 cell growth inhibitor;cetermin;G-TSF;glioblastoma-derived T-cell suppressor factor;LDS4;polyergin;prepro-transforming growth factor beta-2;TGF-beta2;transforming growth factor beta-2 proprotein
- Extra Details:
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
- Shipping Conditions:
- Blue Ice