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  2. Polyclonal

GTX37416

mGluR1 antibody

Cannot supply to this region.

SKU:
GTX37416
Additional Names:
glutamate metabotropic receptor 1 , GPRC1A , MGLU1 , MGLUR1 , PPP1R85 , SCA44 , SCAR13
Application:
WB, IHC-P
Concentration:
0.5 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
10mM TBS, 0.5% BSA, 25% Glycerol, 0.015% ProClin 300.
Immunogen:
KLH conjugated synthetic peptide derived between 661-740 amino acids of human GRM1
Uniprot:
Q13255
Synonyms:
glutamate receptor, metabotropic 1;GPRC1A;metabotropic glutamate receptor 1;MGLU1;MGLUR1;PPP1R85;protein phosphatase 1, regulatory subunit 85;SCA44;SCAR13
Extra Details:
This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Shipping Conditions:
Blue Ice