GTX36254
CaMKII (oxidized) antibody
Cannot supply to this region.
- SKU:
- GTX36254
- Additional Names:
- CAMK , CAMK-II , CAMKG
- Application:
- WB, IHC-P, IHC-Fr, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Unpurified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Serum, 0.05% Sodium azide.
- Immunogen:
- CaMKII synthetic peptide with oxidized Met281/282
- Extra Details:
- Calcium/calmodulin-dependent protein kinase II (CaMKII) couples increases in Ca2+ to fundamental responses in excitable cells including activation of ion channels, gene transcription and apoptosis. CaMKII is activated by angiotensin II-induced oxidation, which leads to apoptosis in cardiomyocytes. CaMKII activity is also enhanced by pro-oxidant conditions, and the oxidation of paired regulatory domain methionine residues sustains CaMKII activity in the absence of Ca2+/CaM.
- Shipping Conditions:
- Blue Ice