GTX35224
SEK1 / MKK4 antibody
Cannot supply to this region.
- SKU:
- GTX35224
- Additional Names:
- mitogen-activated protein kinase kinase 4 , JNKK , JNKK1 , MAPKK4 , MEK4 , MKK4 , PRKMK4 , SAPKK-1 , SAPKK1 , SEK1 , SERK1 , SKK1
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 300-399 of human MAP2K4 (NP_003001.1).
- Uniprot:
- P45985
- Synonyms:
- c-Jun N-terminal kinase kinase 1;dual specificity mitogen-activated protein kinase kinase 4;JNK-activated kinase 1;JNK-activating kinase 1;JNKK;JNKK1;MAP kinase kinase 4;MAPK/ERK kinase 4;MAPKK 4;MAPKK4;MEK 4;MEK4;MKK4;PRKMK4;SAPK/ERK kinase 1;SAPKK-1;SAPKK1;SEK1;SERK1;SKK1;stress-activated protein kinase kinase 1
- Extra Details:
- This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Shipping Conditions:
- Blue Ice