SPTBN2 antibody [SPTBN2/1583]

Cannot supply to this region.

SKU:: GTX35090
Additional Names:: GTRAP41 , SCA5 , SCAR14 , SPTBN2 , spectrin beta, nonerythrocytic 2 , Spectrin Beta III , spectrin B Beta III , spectrin beta, non-erythrocytic 2
Application:: Flow Cytometry, WB, IHC-P, IF, ICC
Concentration:: 0.2 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: protein a/g purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant fragment (around aa356-475) of human SPTBN2 protein (exact sequence is proprietary)
Clone:: SPTBN2/1583
Uniprot:: O15020
Synonyms:: beta-III spectrin;glutamate transporter EAAT4-associated protein 41;GTRAP41;SCA5;SCAR14;spectrin beta chain, brain 2;spectrin beta chain, non-erythrocytic 2;spectrin beta III sigma 2;spectrin, non-erythroid beta chain 2;spinocerebellar ataxia 5 protein
Extra Details:: Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]

Shipping Conditions:: Blue Ice