Melanoma gp100 antibody [SPM142]

Cannot supply to this region.

SKU:: GTX34834
Additional Names:: D12S53E , ME20 , ME20M , P1 , P100 , PMEL , PMEL17 , SI , SIL , SILV , gp100 , premelanosome protein , Pmel 17
Application:: Flow Cytometry, IHC-P, IF, ICC
Concentration:: 0.2 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: protein a/g purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Extract of pigmented melanoma metastases from lymph nodes
Clone:: SPM142
Uniprot:: P40967
Synonyms:: D12S53E;gp100;ME20;ME20-M;ME20M;melanocyte protein mel 17;melanocyte protein PMEL;melanocyte protein Pmel 17;melanocytes lineage-specific antigen GP100;melanoma-associated ME20 antigen;melanosomal matrix protein17;P1;P100;PMEL17;Premelanosome protein;SI;SIL;SILV;silver locus protein homolog;silver, mouse, homolog of
Extra Details:: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]

Shipping Conditions:: Blue Ice