MALT1 antibody [SPM578]

Cannot supply to this region.

SKU:: GTX34813
Additional Names:: IMD12 , MALT1 , MALT1 paracaspase , MLT , MLT1 , PCASP1
Application:: WB, IHC-P
Concentration:: 0.2 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: protein a/g purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Human MALT1 recombinant fragment (aa701-808)
Clone:: SPM578
Uniprot:: Q9UDY8
Synonyms:: caspase-like protein;IMD12;MALT lymphoma-associated translocation;MALT1 protease;MLT;MLT1;mucosa associated lymphoid tissue lymphoma translocation gene 1;mucosa-associated lymphoid tissue lymphoma translocation protein 1;Paracaspase;paracaspase-1;PCASP1
Extra Details:: This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]

Shipping Conditions:: Blue Ice