CFTR antibody [CFTR/1775R]

Cannot supply to this region.

SKU:: GTX34591
Additional Names:: ABC35 , ABCC7 , CF , CFTR , CFTR/MRP , MRP7 , TNRCFTR , cystic fibrosis transmembrane conductance regulator , dJ760C5.1 , CF transmembrane conductance regulator
Application:: IHC-P
Concentration:: 0.2 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant fragment (around aa 258-385) of human CFTR protein (exact sequence is proprietary)
Clone:: CFTR/1775R
Uniprot:: P13569
Synonyms:: ABC35;ABCC7;ATP-binding cassette sub-family C member 7;cAMP-dependent chloride channel;CF;CFTR/MRP;channel conductance-controlling ATPase;cystic fibrosis transmembrane conductance regulating;cystic fibrosis transmembrane conductance regulator;cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7);dJ760C5.1;MRP7;TNR-CFTR
Extra Details:: This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. [provided by RefSeq, Aug 2017]

Shipping Conditions:: Blue Ice