![CD162 antibody [PSGL1/1601]](https://www.genetex.com/upload/website/prouct_img/normal/GTX34468/GTX34468_20200115_IHC-P_1156_w_23060801_237.webp)
![CD162 antibody [PSGL1/1601]](https://www.genetex.com/upload/website/prouct_img/normal/GTX34468/GTX34468_20200115_IHC-P_1289_w_23060801_152.webp)
GTX34468
CD162 antibody [PSGL1/1601]
Cannot supply to this region.
- SKU:
- GTX34468
- Additional Names:
- CD162 , CLA , PSGL1 , SELPLG , selectin P ligand , PSGL-1
- Application:
- IHC-P
- Concentration:
- 0.2 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- protein a/g purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS, 0.05% BSA, 0.05% Sodium azide.
- Immunogen:
- Recombinant human SELPLG (CD162) protein
- Clone:
- PSGL1/1601
- Uniprot:
- Q14242
- Synonyms:
- CD162;CLA;cutaneous lymphocyte-associated associated antigen;P-selectin glycoprotein ligand 1;PSGL-1;PSGL1;Selectin P ligand
- Extra Details:
- This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
- Shipping Conditions:
- Blue Ice