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  2. Monoclonal

GTX34039

HIF1 beta antibody [4C5]

Cannot supply to this region.

SKU:
GTX34039
Additional Names:
ARNT,HIF1B,HIF1BETA,HIF1beta,TANGO,aryl hydrocarbon receptor nuclear translocator,bHLHe2,HIF1 beta
Application:
WB, IHC-P
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human, Mouse
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Mouse
Buffer:
PBS, 0.5% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant Protein
Clone:
4C5
Uniprot:
P27540
Synonyms:
aryl hydrocarbon receptor nuclear translocator;bHLHe2;class E basic helix-loop-helix protein 2;dioxin receptor, nuclear translocator;HIF-1-beta;HIF-1beta;HIF1-beta;HIF1B;HIF1BETA;Hypoxia-inducible factor 1-beta;hypoxia-inducible factor 1, beta subunit;TANGO
Extra Details:
This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
Shipping Conditions:
Blue Ice