GTX33966
GLCNE antibody
Cannot supply to this region.
- SKU:
- GTX33966
- Additional Names:
- DMRV,GLCNE,GNE,IBM2,NM,Uae1,glucosamine (UDPNacetyl)2epimerase/Nacetylmannosamine kinase,glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
- Application:
- WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human, Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- PBS, 0.5% BSA, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Synthesized peptide derived from human GLCNE at 570-650 aa, C-terminal.
- Uniprot:
- Q9Y223
- Synonyms:
- bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase;DMRV;GLCNE;IBM2;N-acylmannosamine kinase;NM;Uae1;UDP-GlcNAc-2-epimerase/ManAc kinase;UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
- Extra Details:
- The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice