GTX33539
TdT antibody
Cannot supply to this region.
- SKU:
- GTX33539
- Additional Names:
- DNA nucleotidylexotransferase , TDT
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human, Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 260-509 of human DNTT (NP_004079.3).
- Uniprot:
- P04053
- Synonyms:
- DNA nucleotidylexotransferase;nucleosidetriphosphate:DNA deoxynucleotidylexotransferase;TDT;terminal addition enzyme;terminal deoxynucleotidyltransferase;terminal deoxyribonucleotidyltransferase;terminal transferase
- Extra Details:
- This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice