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  2. Polyclonal

GTX33374

OGDH antibody

Cannot supply to this region.

SKU:
GTX33374
Additional Names:
oxoglutarate dehydrogenase , AKGDH , E1k , OGDC
Application:
WB, IHC-P, IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 148-427 of human OGDH (NP_001003941.1).
Uniprot:
Q02218
Synonyms:
2-oxoglutarate dehydrogenase complex component E1;2-oxoglutarate dehydrogenase, mitochondrial;AKGDH;Alpha-ketoglutarate dehydrogenase;E1k;KGD1;OGDC;OGDC-E1;OGDH2;oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide);oxoglutarate decarboxylase;oxoglutarate dehydrogenase (succinyl-transferring);testicular tissue protein Li 131
Extra Details:
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
Shipping Conditions:
Blue Ice