GTX33110
COQ3 antibody
Cannot supply to this region.
- SKU:
- GTX33110
- Additional Names:
- coenzyme Q3, methyltransferase , DHHBMT , DHHBMTASE , UG0215E05 , bA9819.1
- Application:
- WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-369 of human COQ3 (NP_059117.3).
- Uniprot:
- Q9NZJ6
- Synonyms:
- 2-polyprenyl-6-hydroxyphenol methylase;2-polyprenyl-6-hydroxyphenyl methylase;3-demethylubiquinol 3-O-methyltransferase;3-demethylubiquinone-10 3-methyltransferase;3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase;bA9819.1;coenzyme Q3 homolog, methyltransferase;DHHB methyltransferase;DHHB-MTase;DHHBMT;DHHBMTASE;dihydroxyhexaprenylbenzoate methyltransferase;hexaprenyldihydroxybenzoate methyltransferase, mitochondrial;methyltransferase COQ3;polyprenyldihydroxybenzoate methyltransferase;ubiquinone biosynthesis O-methyltransferase, mitochondrial;UG0215E05
- Extra Details:
- Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008]
- Shipping Conditions:
- Blue Ice