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  2. Polyclonal

GTX32895

SPTLC1 antibody

Cannot supply to this region.

SKU:
GTX32895
Additional Names:
serine palmitoyltransferase long chain base subunit 1 , HSAN1 , HSN1 , LBC1 , LCB1 , SPT1 , SPTI
Application:
WB, IHC-P
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 37-310 of human SPTLC1 (NP_006406.1).
Uniprot:
O15269
Synonyms:
HSAN1;HSN1;LBC1;LCB1;long chain base biosynthesis protein 1;serine C-palmitoyltransferase;serine palmitoyltransferase 1;serine-palmitoyl-CoA transferase 1;SPT1;SPTI
Extra Details:
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013]
Shipping Conditions:
Blue Ice