GTX32863
Seladin 1 antibody
Cannot supply to this region.
- SKU:
- GTX32863
- Additional Names:
- 24-dehydrocholesterol reductase , DCE , Nbla03646 , SELADIN1 , seladin-1
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 227-516 of human DHCR24 (NP_055577.1).
- Uniprot:
- Q15392
- Synonyms:
- 24-dehydrocholesterol reductase;3 beta-hydroxysterol delta 24-reductase;3-beta-hydroxysterol Delta-24-reductase;DCE;delta(24)-sterol reductase;desmosterol-to-cholesterol enzyme;diminuto/dwarf1 homolog;Nbla03646;seladin 1;seladin-1;SELADIN1;selective AD indicator 1
- Extra Details:
- This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice