GTX32819
PSMC5 antibody
Cannot supply to this region.
- SKU:
- GTX32819
- Additional Names:
- proteasome 26S subunit, ATPase 5 , S8 , SUG-1 , SUG1 , TBP10 , TRIP1 , p45 , p45/SUG
- Application:
- WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 127-406 of human PSMC5 (NP_002796.4).
- Uniprot:
- P62195
- Synonyms:
- 26S protease regulatory subunit 8;26S proteasome AAA-ATPase subunit RPT6;26S proteasome regulatory subunit 8;MSUG1 protein;p45;p45/SUG;proteasome (prosome, macropain) 26S subunit, ATPase, 5;proteasome 26S ATPase subunit 5;Proteasome 26S subunit ATPase 5;proteasome subunit p45;RPT6;S8;SUG-1;SUG1;Tat-binding protein homolog 10;TBP10;testicular tissue protein Li 149;thyroid hormone receptor-interacting protein 1;thyroid receptor interactor 1;TRIP1
- Extra Details:
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
- Shipping Conditions:
- Blue Ice