GTX32700
LAT antibody
Cannot supply to this region.
- SKU:
- GTX32700
- Additional Names:
- linker for activation of T cells , IMD52 , LAT1 , pp36
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 28-233 of human LAT (NP_001014987.1).
- Uniprot:
- O43561
- Synonyms:
- 36 kDa phospho-tyrosine adapter protein;36 kDa phospho-tyrosine adaptor protein;IMD52;LAT1;linker for activation of T cells, transmembrane adaptor;linker for activation of T-cells family member 1;p36-38;pp36
- Extra Details:
- The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice