GTX32562
DKC1 antibody
Cannot supply to this region.
- SKU:
- GTX32562
- Additional Names:
- dyskerin pseudouridine synthase 1 , CBF5 , DKC , DKCX , NAP57 , NOLA4 , XAP101
- Application:
- WB, IHC-P, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 245-514 of human DKC1 (NP_001354.1).
- Uniprot:
- O60832
- Synonyms:
- CBF5;CBF5 homolog;DKC;DKCX;dyskeratosis congenita 1, dyskerin;Dyskerin;H/ACA ribonucleoprotein complex subunit 4;H/ACA ribonucleoprotein complex subunit DKC1;NAP57;NOLA4;nopp140-associated protein of 57 kDa;nucleolar protein family A member 4;nucleolar protein NAP57;snoRNP protein DKC1;XAP101
- Extra Details:
- This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
- Shipping Conditions:
- Blue Ice