GTX32519
CHIT1 antibody
Cannot supply to this region.
- SKU:
- GTX32519
- Additional Names:
- chitinase 1 , CHI3 , CHIT , CHITD
- Application:
- WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 217-466 of human CHIT1 (NP_003456.1).
- Uniprot:
- Q13231
- Synonyms:
- CHI3;CHIT;CHITD;chitinase 1 (chitotriosidase);Chitinase-1;chitotriosidase-1;plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
- Extra Details:
- Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]
- Shipping Conditions:
- Blue Ice