GTX32462
Autotaxin antibody
Cannot supply to this region.
- SKU:
- GTX32462
- Additional Names:
- ectonucleotide pyrophosphatase/phosphodiesterase 2 , ATX , ATX-X , AUTOTAXIN , LysoPLD , NPP2 , PD-IALPHA , PDNP2
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 564-863 of human ENPP2 (NP_001035181.1).
- Uniprot:
- Q13822
- Synonyms:
- ATX;ATX-X;AUTOTAXIN;autotaxin-t;E-NPP 2;ectonucleotide pyrophosphatase/phosphodiesterase family member 2;extracellular lysophospholipase D;LysoPLD;NPP2;PD-IALPHA;PDNP2;phosphodiesterase I/nucleotide pyrophosphatase 2;plasma lysophospholipase D
- Extra Details:
- The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
- Shipping Conditions:
- Blue Ice