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  2. Polyclonal

GTX32187

GRB10 (phospho Tyr67) antibody

Cannot supply to this region.

SKU:
GTX32187
Additional Names:
growth factor receptor bound protein 10 , GRB-IR , Grb-10 , IRBP , MEG1 , RSS
Application:
WB, IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
Immunogen:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of GRB10. The exact sequence is proprietary.
Uniprot:
Q13322
Synonyms:
Grb-10;GRB-IR;GRB10 adapter protein;GRB10 adaptor protein;growth factor receptor-bound protein 10;insulin receptor-binding protein Grb-IR;IRBP;maternally expressed gene 1;MEG1;RSS
Extra Details:
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Shipping Conditions:
Blue Ice