GTX32158-PEP
PACS1 blocking peptide
Cannot supply to this region.
- SKU:
- GTX32158-PEP
- Additional Names:
- Phosphofurin Acidic Cluster Sorting Protein 1 , Mrd17 , Shms , Pacs1
- Application:
- Neutralisation
- Concentration:
- 200 ug/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- phosphofurin acidic cluster sorting protein 1
- Species:
- Human
- Synonyms:
- cytosolic sorting protein PACS-1;MRD17;PACS-1;phosphofurin acidic cluster sorting protein 1;SHMS
- Extra Details:
- This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Dry Ice